In the context of infectious diseases in mollusc and shrimp aquacultur
e, research must be focused on diagnosis for zoosanitary controls but
also on obtaining resistant animals. This last strategy depends heavil
y on the development of knowledge about marine invertebrate immunology
. With the establishment of purification protocols for the main invert
ebrate pathogens, progress has been made in the study of host-pathogen
interactions at cellular and molecular levels and in identifying immu
ne effecters involved in the destruction of pathogens. Recent informat
ion on molluscs and crustaceans is presented, concerning both hemocyte
studies and cellular defence functions and humoral effecters, with sp
ecial reference to their application to selection of pathogen-resistan
t animals. With this aim, research prospects will essentially be devot
ed to the identification and characterization of immune genes, either
specific or heterologous, which could be candidates for mollusc and sh
rimp genetic transformation.