S. Twetman et al., EFFECT OF AN ANTIBACTERIAL VARNISH ON MUTANS STREPTOCOCCI IN PLAQUE FROM ENAMEL ADJACENT TO ORTHODONTIC APPLIANCES, Caries research, 29(3), 1995, pp. 188-191
The effect of an antibacterial varnish (Cervitec(R)) on the levels of
mutans streptococci in plaque adjacent to bonded orthodontic brackets
was evaluated in 18 children using a split-mouth technique with a plac
ebo varnish control. The test varnish contained 1% chlorhexidine and 1
% thymol as active ingredients. Both varnishes were applied on four oc
casions during a 3-month period, and plaque was subsequently collected
between 1 week and 6 months after the onset of treatment. All teeth i
nvolved in the study were carefully examined and clinically assessed f
or enamel demineralization prior to onset of the fixed appliances and
immediately after debonding. The results showed a more frequent growth
of mutans streptococci in the dental plaque collected from placebo-tr
eated quadrants as compared with the test quadrants on all sampling oc
casions. The proportion of mutans streptococci within the plaque micro
flora was significantly (p < 0.05-0.01) lower on the test sides than o
n the opposite sides at the 1-week and I-month examinations. The incid
ence of incipient enamel lesions around the brackets and along the gin
gival margin was generally low, and no differences were found between
the test and placebo varnish treated quandrants at the time of debondi
ng. The results suggest that mutans streptococci in plaque from orthod
ontic patients can be suppressed effectively by topical applications o
f an antibacterial, varnish.