Hr. Khouzam et al., TREATMENT OF CRACK-COCAINE-INDUCED COMPULSIVE BEHAVIOR WITH TRAZODONE, Journal of substance abuse treatment, 12(2), 1995, pp. 85-88
Foraging is a compulsive behavior of searching for pieces of crack coc
aine that the individual believes might have been accidentally misplac
ed. Three clinical cases of compulsive foraging behavior associated wi
th crack cocaine are described. Due to the development of side effects
secondary to the antidepressant desipramine, the patients were switch
ed to the antidepressant trazodone. The use of trazodone led to remiss
ion of the foraging behavior. The authors hypothesize this remission w
as due to trazodone serotonin reuptake inhibitory action. In all three
cases, the patients did not relapse into abusing crack cocaine.