MICROBIAL ALKENE EPOXIDATION - MERITS AND LIMITATIONS

Authors
ONUMONU AN COLOCOUSSI A MATTHEWS C WOODLAND MP LEAK DJ
Citation
An. Onumonu et al., MICROBIAL ALKENE EPOXIDATION - MERITS AND LIMITATIONS, Biocatalysis, 10(1-4), 1994, pp. 211-218
Citations number
23
Categorie Soggetti
Biology,"Biothechnology & Applied Migrobiology
Journal title
Biocatalysis → ACNP
ISSN journal
08864454
Volume
10
Issue
1-4
Year of publication
1994
Pages
211 - 218
Database
ISI
SICI code
0886-4454(1994)10:1-4<211:MAE-MA>2.0.ZU;2-R
Abstract
The direct epoxidation of olefins using monooxygenases offers the real istic prospect of stoichiometric conversion of a pro-chiral substrate into an enantiomerically pure product. A number of microbial systems a re available in which the mechanism of oxygen activation, and conseque ntly the oxygen reactivity, differs. This paper discusses some of the merits and potential problems associated with these different systems.