D. Schmoll et al., COLOCALIZATION OF FRUCTOSE-1,6-BISPHOSPHATASE AND GLIAL FIBRILLARY ACIDIC PROTEIN IN RAT-BRAIN, Brain research, 677(2), 1995, pp. 341-344
Immunofluorescence studies of rat brain sections demonstrated an exclu
sive colocalization of the gluconeogenic key enzyme fructose-1,6-bisph
osphatase (FBPase) with the astroglial marker glial fibrillary acidic
protein, indicating FBPase in brain as an astrocyte-specific enzyme. T
his conclusion was supported by the presence of FBPase activity in ast
roglia-rich but not neuron-rich primary cultures derived from rat brai
n.