Ta. Lieu et al., COMPUTER-GENERATED RECALL LETTERS FOR UNDERIMMUNIZED CHILDREN - HOW COST-EFFECTIVE, The Pediatric infectious disease journal, 16(1), 1997, pp. 28-33
Objective. To evaluate the effectiveness and cost effectiveness of com
puter-generated recall letters to parents of children overdue for immu
nizations. Methods. This randomized controlled trial included children
of two facilities in a regional health maintenance organization. Pare
nts of 20-month-olds who had not yet received a measles-mumps-rubella
(MMR) immunization were identified via a computerized immunization tra
cking system. One half were mailed personalized letters that included
the recommended immunization schedule and a request to call for an app
ointment; the other half served as a control group. Receipt of the MMR
between 28 and 24 months of age was evaluated with the computerized t
racking system, a telephone survey was conducted with parents whose ch
ildren had not received the MMR by 24 months. Decision analysis was us
ed to project the theoretical outcomes and costs of a recall letter po
licy for other populations. Results. Among 20-month-old children 10% h
ad not received the MMR; 289 families were included in the analysis. O
f families who were mailed letters, 54% (82 of 153) received the MMR b
y 24 months of age, compared with 35% (47 of 136) of those in the cont
rol group (P = 0.001). The telephone survey was completed with 110 par
ents of children who still did not appear on the health plan computer
as having received the MMR by 24 months. Fifteen percent said the chil
d had received an immunization at an outside provider and of the rest
62% said they had not been aware that an immunization was due. In the
cost effectiveness analysis it was project;ed that recall letters woul
d increase the immunization rate for the regional population of approx
imately 30 000 children from 86% to 90% at a total cost of $5031 annua
lly. The cost per additional child appropriately immunized was $4.04.
In sensitivity analyses this cost effectiveness ratio varied depending
on the baseline population coverage rate as well as the estimated eff
ectiveness of recall letters. Conclusions. Computer-generated letters
to recall children overdue for immunizations resulted in a higher prop
ortion of children appropriately immunized in this setting. However, t
he strategy was not as cost-effective as intuition might suggest. Furt
her studies in health maintenance organization (HMO) settings should c
ompare the cost effectiveness of letters with other low cost strategie
s including automated telephone reminders.