MODELING THE REACTIVITY OF ALPHA-KETOGLUTARATE-DEPENDENT NONHEME IRON(II)-CONTAINING ENZYMES

Authors
HA EH HO RYN KISIEL JF VALENTINE JS
Citation
Eh. Ha et al., MODELING THE REACTIVITY OF ALPHA-KETOGLUTARATE-DEPENDENT NONHEME IRON(II)-CONTAINING ENZYMES, Inorganic chemistry, 34(9), 1995, pp. 2265-2266
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Inorganic chemistry → ACNP
ISSN journal
00201669
Volume
34
Issue
9
Year of publication
1995
Pages
2265 - 2266
Database
ISI
SICI code
0020-1669(1995)34:9<2265:MTROAN>2.0.ZU;2-8
Abstract
An Fe(II) complex of tris(pyrazolyl)borate and benzoylformate was prep ared and reacted with dioxygen in the presence of olefins. In the caes of cyclohexene, cyclohexene oxide was produced in 35-40% yield. In th e case of cis- and trans-stilbene, the former was found to react to gi ve cis-stilbene oxide in 50-60% yield and a small amount of benzaldehy de; no trans-oxide was observed. The latter gave no reaction. This sys tem is proposed as a possible model for reactions of alpha-ketoglutara te-dependent Fe(II)-containing dioxygenase enzymes. [GRAPHICS]