Sm. Kasper et al., THE ROLE OF AUTOLOGOUS BLOOD-TRANSFUSION IN THE FEDERAL-REPUBLIC-OF-GERMANY - RESULTS OF A 1993 QUESTIONNAIRE .1. THE REUNITED GERMANY, Anasthesist, 44(4), 1995, pp. 230-241
The objective of the study was to evaluate the role of autologous bloo
d transfusion in current clinical practice in the Federal Republic of
Germany after reunification. Methods. Questionnaires were sent to the
anaesthesia departments of 684 German hospitals in January 1993. The s
ample consisted of 400 randomly selected hospitals from the former Wes
t Germany (''old federal states'') and 284 hospitals from the former G
erman Democratic Republic (''new federal states''). Only hospitals wit
h more than 25 surgical beds were included in the study. The questionn
aire contained 36 questions related to (1) general information on the
hospital, (2) preoperative autologous blood donation (PABD), (3) preop
erative plasmapheresis, (4) isovolaemic haemodilution, (5) perioperati
ve blood salvage, and (6) general management of blood transfusion. Res
ults. A total of 502 completed questionnaires (73%) were returned, 305
from hospitals in the ''old federal states'' and 197 from hospitals i
n the former German Democratic Republic. Nine per cent of the respondi
ng hospitals were running their own transfusion services, and 56% were
located in the vicinity of a regional blood bank. The overall proport
ion of surgical procedures requiring perioperative blood transfusion r
anged from 1% to 90% (median 10%). PABD was performed ''not at all'' i
n 18%, ''rarely'' in 20% ''occasionally'' in 27%, ''frequently'' in 17
%, and ''mostly'' in 16% of the responding hospitals. The principal us
e of PABD was in orthopaedic surgery and cardiac surgery (83% and 70%
of the departments in question, respectively). In more than 50% of the
hospitals reporting, the PABD service was run by the anaesthesia depa
rtment. Patients not meeting the established criteria for homologous b
lood donors were accepted for autologous blood donation ''frequently''
and ''mostly'' in 20% and 12% of the hospitals, respectively, but at
most ''occasionally'' in 63% of the hospitals. Preoperative plasmapher
esis was performed in 12% of the responding hospitals. Autologous fres
h frozen plasma predominantly was used for volume replacement, and for
prevention of coagulation disorders when major blood loss was anticip
ated. Isovolaemic haemodilution was performed ''not at all'' in 28%, '
'rarely'' in 19%, ''occasionally'' in 28%, ''frequently'' in 16%, and
''mostly'' in 8% of the responding hospitals. The reasons most frequen
tly invoked for not performing haemodilution were ''too time consuming
'' and ''too little blood-saving effect''. Cell separators for periope
rative blood salvage were available in 30% of the responding hospitals
. Of the other hospitals not equipped with cell-washing devices, 11% p
erformed perioperative blood salvage of unprocessed blood by means of
simple collection devices. Some 80% of those hospitals using intraoper
ative autotransfusion devices also performed blood salvage postoperati
vely. The principal use of perioperative blood salvage was in cardiac
surgery, orthopaedics, and vascular surgery (90%, 54%, and 54% of depa
rtments, respectively). Some 48% of the responding anaesthetists ''mos
tly'' considered haemoglobin levels of 8-10 g/dl acceptable in patient
s without cardiopulmonary disease, but only 18% did so in patients wit
h cardiopulmonary disease. Conclusions. Although available in the majo
rity of hospitals surveyed, the simple techniques of both PABD and iso
volaemic haemodilution are unduly neglected in routine clinical practi
ce. The consistent use of both of these techniques, and the careful we
ighing up of the indication for every single blood transfusion, would
not only effectively reduce homologous blood transfusions, but also en
able even small hospitals to run successful autologous transfusion pro
grammes without expensive cell-washing and plasmapheresis devices.