APPLICATION OF HPLC AND CZE TO THE ANALYSIS OF POLYOXOMETALATES

Polyoxometalates (POM) are polymers of transition metal oxides. They a re widely used as analytical reagents and reaction catalysts. Some hav e anti-viral properties and are being investigated as anti-HIV agents. Due to solubility and stability limitations, separation methods for P OM are rare in the literatures. This paper presents a HPLC and a CZE m ethod for the analysis of sodium tungstate, its equilibrium products a nd isopolyanions. The methods are simple and sensitive, and can be use d to monitor the purity, stability and solution equilibria of POM.