Yc. Leung et al., DETERMINATION OF THE MINERAL PHASES AND STRUCTURE OF THE BONE-IMPLANTINTERFACE USING RAMAN-SPECTROSCOPY, Journal of biomedical materials research, 29(5), 1995, pp. 591-594
The bone-implant interface formed in a canine distal femur was examine
d by means of a Raman microprobe using an implant model designed to te
st calcium phosphate surface coatings. By using the 960 cm(-1) band of
calcium phosphate to characterize the interface and adjacent mineral,
we obtained spatial and compositional information about the attachmen
t of bone to the synthetic calcium phosphate coating on a titanium sup
port. The interface between bone and the synthetic calcium phosphate i
s approximately 30-40 mu m in width. (C) 1995 John Wiley and Sons, Inc
.