COMPLICATIONS CAUSED BY HYPERTHERMIC ISOL ATED LIMB PERFUSION FOR REGIONAL TREATMENT OF MALIGNANT MELANOMAS - CLINICAL-EXPERIENCE WITH A RECURRENT MALIGNANT-MELANOMA OF THE FEET IN CASE OF A 20-YEAR-OLD PATIENT

A hyperthermic isolated limb perfusion (HILP) via A. femoralis communi s with cisplatin and melphalan over a period of 6 weeks has caused an occlusion of the A. iliaca externa, A. femoralis superficialis, and A, tibialis anterior in the case of a 20-year old female patient with re current malignant melanoma of the regio calcanea, a chemotoxic infecti on of the arteries and the adventitia was caused by HILP. As a presupp osition for reconstructive surgery with transplantation of the muse. l atissimus dorsi after resection of the recurrent melanoma it was neces sary to implantate a jump graft as an iliaco-profundal-popliteal-saphe na bypass. Finally then has been no chance for reconstructive surgery because of the rapid tumor progress.