Two hundred thirty-nine patients with benign prostatic hyperplasia (BP
H) were treated using interstitial laser coagulation (ILC or LITT; las
er-induced interstitial thermotherapy), and the long-term results were
determined. In this minimally invasive procedure, special laser light
guides were inserted into the adenoma tissue in order to achieve prim
ary large-volume coagulation necrosis and secondary shrinking, leaving
the urethra intact. The AUA Symptom Scores improved markedly, from an
average of 25 pretreatment to an average of 6 at 1 year. Peak urine f
low rates improved commensurably, from 8 mL/sec pretreatment to 18 mL/
sec at 1 year. Postoperative irritative symptoms occurred occasionally
, affecting only 12% of patients. Significant complications were rare,
with 4% of patients suffering strictures and 7% retrograde ejaculatio
n. No patients suffered impotence or incontinence. Only 9.6% of patien
ts required retreatment for BPH during 12 months of follow-up. Twelve
patients were treated with subsequent transurethral laser incision of
the bladder neck in order to shorten the time required for improvement
of voiding function.