Background: It is known that Wegener's granulomatosis may affect the e
ye, but macroscopically visible granulomas in patients with this condi
tion have not yet been described. Methods: Results of clinical, ultras
ound, and histologic examination of a patient with Wegener's granuloma
tosis are presented. Results: A sclerochoroidal granuloma in this pati
ent simulated an uveal melanoma. It was not possible to unequivocally
differentiate the lesion from a uveal melanoma on sonographic examinat
ion, but histologic examination confirmed the diagnosis of sclerochoro
idal granuloma. Conclusion: Macroscopically visible sclerochoroidal gr
anuloma is another facet of Wegener's granulomatosis, and in some case
s may be mistaken for uveal melanoma.