Sclerodactyly is a chronic skin disorder seen together with long-term
degenerative microvascular complications of diabetes mellitus, In this
study, the relationship between sclerodactyly and various clinical an
d laboratory characteristics of diabetes mellitus have been investigat
ed, One hundred and forty-two diabetic patients (63 type 1 and 79 type
2) and 72 healthy controls were evaluated clinically. Among the 142 d
iabetic patients, skin biopsies were taken from 21; 38 underwent soft
tissue X-ray examination and 78 underwent periungual capillaroscopy. A
mong the healthy controls those with sclerodactyly were on the average
12 years older than those without (T:3.38; P < 0.01). On the other ha
nd, among the patients with either type 1 or type 2 diabetes mellitus
the ages were similar between those with and without sclerodactyly. Th
ere were no statistically significant differences in the prevalence of
diabetic complications, The presence of complications, increased prox
imal nail fold capillarity, HbA(1c) levels, radiological and histopath
ological findings were not different among those patients who had oi d
id not have sclerodactyly.