Hn. Christensen et M. Kilberg, HEPATIC AMINO-ACID-TRANSPORT PRIMARY TO THE UREA CYCLE IN REGULATION OF BIOLOGIC NEUTRALITY, Nutrition reviews, 53(3), 1995, pp. 74-76
A biologic determination appears to be made as to whether the nitrogen
ous portion of food amino acids reaches the kidney for excretion as am
monium ion, or whether it is sent to the liver to form urea. It now be
comes likely that this determination occurs primarily by hydrogen ion
inhibition of at least one transport system by which the liver receive
s amino acids, and not by regulation applied directly to the liver-orn
ithine cycle.