Me. Gross et al., ANTIMICROBIAL ACTIVITIES OF BETA-LACTAM ANTIBIOTICS AND GENTAMICIN AGAINST PENICILLIN-SUSCEPTIBLE AND PENICILLIN-RESISTANT PNEUMOCOCCI, Antimicrobial agents and chemotherapy, 39(5), 1995, pp. 1166-1168
The MICs of penicillin and cefotaxime for a range of penicillin-suscep
tible and penicillin-resistant isolates of Streptococcus pneumoniae we
re unchanged by the addition of gentamicin. In time-kill studies the r
ate of killing was greater for 18 of 20 isolates in the presence of ge
ntamicin. However, mean differences in killing after 6 h of incubation
were modest, not exceeding 1 log(10) unit.