A SHORT ROUTE TO ENANTIOMERICALLY PURE NARCICLASINE DERIVATIVES

Authors
KHALDI M CHRETIEN F CHAPLEUR Y
Citation
M. Khaldi et al., A SHORT ROUTE TO ENANTIOMERICALLY PURE NARCICLASINE DERIVATIVES, Tetrahedron letters, 36(17), 1995, pp. 3003-3006
Citations number
43
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
17
Year of publication
1995
Pages
3003 - 3006
Database
ISI
SICI code
0040-4039(1995)36:17<3003:ASRTEP>2.0.ZU;2-1
Abstract
Condensation of substituted O-toluamide anions on to di-O-isopropylide ne D-gulono-1,4-lactone followed by intramolecular aldol cyclisation p rovides 2-aryl-cyclohexenones which were in turn transformed into prot ected forms of 4a-epi-narciclasine and iso-narciclasine via a reductiv e amination.