ASSESSMENT OF THE EFFICACY OF OXFENDAZOLE AGAINST TRICHURIS-VULPIS INDOGS

The anthelmintic activity of oxfendazole at a dose rate of 11,3 mg/kg/ day for three consecutive days administered by oral route during feedi ng was assessed through two <<control tests>>. Fourteen seven months o ld Beagle dogs were experimentally infected each with 500 embryonnated eggs, and treated on 83rd, 84th and 85th days post-infestation. At ne cropsy, 75,6 whipworms on average were found in the control dogs where as 1,4 on average was found in the treated group. Consequently, the ef ficacy was 98,1 %. In the second study, fifteen Beagle dogs naturally infested by Trichuris vulpis were treated with the same protocol. AL n ecropsy, 18,5 whipworms on average were found in the control dogs wher eas 0,9 on average was found in the treated group, showing a 95,1 % ef ficacy. Treatments were fully accepted by dogs and very well tolerated .