The prefabricated induced expanded (PIE) supraclavicular flap refers t
o the staged transfer of an expanded supraclavicular skin with a fasci
a flap used as the carrier. In three patients, we utilized PIE supracl
avicular flaps to successfully reconstruct a total forehead and mio ma
jor nasal defects. Our first PIE flap confirmed the feasibility of the
method but necessitated two microvascular free flaps. In the ensuing
two patients, we reduced the need for microvascular anastomoses by usi
ng simple pedicled flap transfers in either or both stages. Whenever f
easible, the preferred method consists of transferring a temporopariet
al fascia flap to a subcutaneous pocket in the ipsilateral supraclavic
ular fossa and simultaneously placing a skin expander under both the f
ascia flap and the supraclavicular skin. After adequate expansion, the
fascia becomes incorporated within the capsule of the expander, and t
he composite capsulofasciocutaneous flap can be safely transferred to
the facial defect as the PIE flap.These patients show that supraclavic
ular PIE flaps can provide ample amounts of vascularized cutaneous tis
sue for the reconstruction of major facial defects. The necessary tiss
ue is generated by expanding the most desirable tissue type available,
and a selected vascular pedicle is induced to perfuse and carry that
generated tissue. Compared with conventional expansion and adjacent fl
ap transfers, PIE flaps allow the transfer of expanded skin to distant
sites as island or free flaps perfused by the induced vascular pedicl
es.