A HUMAN BONE-MARROW CELL-CULTURE - A SENS ITIVE METHOD BY JUDGMENT OFTHE BIOCOMPATIBILITY OF MATERIALS, WHICH ARE USED IN ORTHOPEDIC-SURGERY

Authors
WILKE A VONHIRSCHHEYDT S ORTH J KIENAPFEL H GRISS P FRANKE RP
Citation
A. Wilke et al., A HUMAN BONE-MARROW CELL-CULTURE - A SENS ITIVE METHOD BY JUDGMENT OFTHE BIOCOMPATIBILITY OF MATERIALS, WHICH ARE USED IN ORTHOPEDIC-SURGERY, Zeitschrift fur Orthopadie und Ihre Grenzgebiete, 133(2), 1995, pp. 159-165
Citations number
NO
Categorie Soggetti
Orthopedics
Journal title
Zeitschrift fur Orthopadie und Ihre Grenzgebiete → ACNP
ISSN journal
00443220
Volume
133
Issue
2
Year of publication
1995
Pages
159 - 165
Database
ISI
SICI code
0044-3220(1995)133:2<159:AHBC-A>2.0.ZU;2-4
Abstract
The objective of the study was to develop a test system to determine t he cytotoxicity and biocompatibility of different biomaterials used in orthopedic surgery. This system was based on the use of a human bone marrow cell culture and the purpose was to find a screening method as a alternative to early animal experimental methods. The established hu man bone marrow cell culture has certain advantages when compared with other cell culture models. The result demonstrated a high conformity with animal experimental results.