PATHOPHYSIOLOGY AND TREATMENT OF THE ANEMIA OF PREMATURITY

Increased understanding of the pathophysiology of anemia of prematurit y (AOP) has emerged over the past years. It is apparent that low level s of endogenous erythropoietin (Epo) is the basis for this phenomenon. This has resulted in an effective therapeutic approach for this condi tion. Administration of Epo can ameliorate the signs and symptoms of A OP and lessen, and in many cases avoid, the necessity for blood transf usion.