The purpose of this report is to draw attention to haemodynamic change
s during intraoperative adrenal gland manipulation. Severe hypertensio
n, ventricular tachycardia and subendocardial ischaemia occurred durin
g the manipulation of adrenal gland in a patient who underwent live re
lated donor nephrectomy. The patient responded well to intravenous lid
ocaine. Plasma norepinephrine concentration was elevated at the time o
f event. Further investigations after surgery excluded the possibility
of phaeochromocytoma. In two years follow-up patient remains well. Su
spicion for the cause of the event remains the excessive release of ca
techolamines with manipulation of a normal adrenal gland. The presence
of halothane might have contributed to the arrythmia.