Qs. Wang et al., COMPUTER-ASSISTED OPTIMIZATION OF PESTICIDES SEPARATION BY 2-DIMENSIONAL HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY, Chromatographia, 40(7-8), 1995, pp. 463-466
A computer-assisted method is presented for optimization of two mobile
phase selection for separation of a mixture of eight pesticides in tw
o-dimensional TLC. Optimization of the separation over the experimenta
l region is based on two special polynomial estimations from prelimina
ry runs of two groups. Using D (distance of two spots) as the selectio
n criterion with a two factor statistical scanning technique excellent
agreement is obtained between predicted and experimental results.