PHYSICAL FACTORS AFFECTING THE SPORICIDAL ACTIVITY OF CHLORHEXIDINE GLUCONATE

Authors
JONES DS LOFTUS AM GORMAN SP
Citation
Ds. Jones et al., PHYSICAL FACTORS AFFECTING THE SPORICIDAL ACTIVITY OF CHLORHEXIDINE GLUCONATE, International journal of pharmaceutics, 119(2), 1995, pp. 247-250
Citations number
14
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
International journal of pharmaceutics → ACNP
ISSN journal
03785173
Volume
119
Issue
2
Year of publication
1995
Pages
247 - 250
Database
ISI
SICI code
0378-5173(1995)119:2<247:PFATSA>2.0.ZU;2-2
Abstract
The effects of pH and indirect ultrasonication on the cidal activity o f aqueous and alcoholic solutions of chlorhexidine gluconate against B acillus subtilis spores were examined. At moderately elevated temperat ures, increasing pH enhanced sporicidal activity. pH markedly enhanced the sporicidal activity between indirect ultrasound and chlorhexidine . 'Alcoholic' chlorhexidine gluconate was more sporicidal than its aqu eous counterpart.