THE STEREOCHEMICAL OUTCOME OF THE DAST FLUORINATION OF 4'-THIOPYRIMIDINE NUCLEOSIDES WITH UP HYDROXYL-GROUPS IS CONTROLLED BY THE OXIDATION-STATE OF THE SULFUR ATOM

Authors
JEONG LS MARQUEZ VE
Citation
Ls. Jeong et Ve. Marquez, THE STEREOCHEMICAL OUTCOME OF THE DAST FLUORINATION OF 4'-THIOPYRIMIDINE NUCLEOSIDES WITH UP HYDROXYL-GROUPS IS CONTROLLED BY THE OXIDATION-STATE OF THE SULFUR ATOM, Chemistry Letters, (4), 1995, pp. 301-302
Citations number
5
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
4
Year of publication
1995
Pages
301 - 302
Database
ISI
SICI code
0366-7022(1995):4<301:TSOOTD>2.0.ZU;2-#
Abstract
DAST fluorination of -3-deoxy-4-thio-beta-D-threo-pentofuranosyl)uraci l proceeds with retention of configuration, while the corresponding su lfoxide gives mainly the inverted product. The sulfone proceeds with e limination.