FASICULARIN, A NOVEL TRICYCLIC ALKALOID FROM THE ASCIDIAN NEPHTEIS-FASICULARIS WITH SELECTIVE ACTIVITY AGAINST A DNA REPAIR-DEFICIENT ORGANISM

Authors
PATIL AD FREYER AJ REICHWEIN R CARTE B KILLMER LB FAUCETTE L JOHNSON RK FAULKNER DJ
Citation
Ad. Patil et al., FASICULARIN, A NOVEL TRICYCLIC ALKALOID FROM THE ASCIDIAN NEPHTEIS-FASICULARIS WITH SELECTIVE ACTIVITY AGAINST A DNA REPAIR-DEFICIENT ORGANISM, Tetrahedron letters, 38(3), 1997, pp. 363-364
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
3
Year of publication
1997
Pages
363 - 364
Database
ISI
SICI code
0040-4039(1997)38:3<363:FANTAF>2.0.ZU;2-F
Abstract
A novel tricyclic alkaloid, fasicularin (1), was isolated from the Mic ronesian ascidian Nephteis fasicularis. The structure of I was elucida ted primarily by interpretation of spectral data. Fasicularin was foun d to be active in a DNA damaging assay. Copyright (C) 1996 Elsevier Sc ience Ltd