We report a case of squamous cell carcinoma of the ileovesical junctio
n 12 years following total replacement of the ureter with ileum. The u
roenteric junctions, which are not exposed to the fecal stream, may be
associated with cancer as in ureterosigmoidostomy. The urine infected
with fecal bacterial flora combined with a healing uroenteric suture
line may be responsible for the tumorigenesis. Urine cytology should b
e performed at least yearly beginning 10 years after ileal ureter. If
any abnormality was suspected cystoscopy must be performed.