Mj. Hilz et al., THERMAL THRESHOLD DETERMINATION IN ALCOHOLIC POLYNEUROPATHY - AN IMPROVEMENT OF DIAGNOSIS, Acta neurologica Scandinavica, 91(5), 1995, pp. 389-393
Reports on the incidence of alcoholic polyneuropathies are variable de
pending on diagnostic tools. In this study, 50 chronic alcoholics with
positive MALT (Munich Alcoholism Test) and greater than seven years h
istory of excessive alcohol abuse were examined neurologically. Tibial
and peroneal motor and sural nerve conduction velocities (NCV) were s
tudied. Warm and cold perception was evaluated in the area behind the
internal malleolus using a Somedic-Thermotest. Thresholds were determi
ned by the method of limits. The effect of a slow, medium and fast tem
perature change rate on thermal perception was tested. Thirty-eight pa
tients (76%) showed signs of neuropathy. Thermal perception was more o
ften abnormal(62%) than NCV (42%) and clinical examination (56%). A me
dium temperature change rate of 2.0-2.5 degrees C/s was the most sensi
tive index of small fiber neuropathy. Thermal threshold measurement pr
oved to be a reliable, sensitive and easy to perform method that shoul
d become standard in the examination of polyneuropathies.