ORDERING AND INTERPRETING DNA TESTS

DNA testing has become relatively common during the past few Fears. Al l humans have an estimated five to eight mutated genes and are at risk for a genetic disorder. Recognition of these facts and development of DNA technology have created substantial interest in DNA testing as a diagnostic and management tool, As with any emerging technology, the a pplications and limitations must be understood in order to use the new tests wisely, In this review, the basic molecular diagnostic techniqu es are discussed, In addition, the emerging ethical debate surrounding the use of this new technology is summarized, Caution is necessary wh en DNA tests are being used, especially in presymptomatic situations.