LYMPHOEPITHELIOMA-LIKE CARCINOMA OF THE SKIN TREATED WITH MOHS MICROGRAPHIC SURGERY IN COMBINATION WITH IMMUNE STAINING FOR CYTOKERATINS

Lymphoepithelioma-like carcinoma of the skin (LLCS) is a rare cutaneou s neoplasm that histologically resembles nasopharyngeal lymphoepitheli oma. Conventional surgical excision carries a considerable rate of rec urrence (three of 11 reported cases with such treatment, with one pati ent dying of metastatic disease). We report the first case of lymphoep ithelioma-like carcinoma of the skin treated with Mohs micrographic su rgery. Because of its tendency to occur on the face and its potential for recurrence after incomplete removal, this tumor is a good candidat e for treatment with Mohs micrographic surgery. Immunohistochemical st aining of frozen sections for cytokeratins may help to detect neoplast ic cells that may be obscured by the dense lymphoplasmacytic infiltrat e associated with this tumor.