R. Stollberger et al., MORPHOLOGY-ORIENTED ANALYSIS OF CEREBRAL SPET USING MATCHED MAGNETIC-RESONANCE IMAGES, Nuclear medicine communications, 16(4), 1995, pp. 265-272
Complementary morphological information is a prerequisite for the deta
iled analysis of cerebral SPET studies. We therefore developed a techn
ique which allows the alignment of SPET and magnetic resonance scans b
y imaging identical slices using external landmarks on an individually
fitted mask and subsequent two-dimensional image processing for in-pl
ane matching. Regional analysis of tracer activities can be performed
directly on the superimposed SPET and MR outline images or by tracing
a region of interest on the original MR scan with a parallel display o
n the matched SPET image, and vice versa. Tests assessing correct in-p
lane alignment using MRI, inter- and intra-variability of the matching
procedure, and its comparability with an objectively determined best-
matching position, confirmed the feasibility, accuracy and usefulness
of this procedure.