NORMAL AGE-RELATED-CHANGES IN THYROID-HORMONE ECONOMY

Authors
MOORADIAN AD
Citation
Ad. Mooradian, NORMAL AGE-RELATED-CHANGES IN THYROID-HORMONE ECONOMY, Clinics in geriatric medicine, 11(2), 1995, pp. 159-169
Citations number
NO
Categorie Soggetti
Medicine, General & Internal","Geiatric & Gerontology
Journal title
Clinics in geriatric medicine → ACNP
ISSN journal
07490690
Volume
11
Issue
2
Year of publication
1995
Pages
159 - 169
Database
ISI
SICI code
0749-0690(1995)11:2<159:NAITE>2.0.ZU;2-9
Abstract
Aging is associated with significant changes in the anatomy of the thy roid gland and in the physiology of hypothalmic-pituitary-hormone thyr oid axis. In addition, tissue responsiveness to thyroid hormone may al so be altered with age. However, ge alone should not influence the int erpretation of commonly obtained thyroid function tests. The reduced t hyroid hormone clearance with age explains the reduced daily replaceme nt doses of thryoxine in hypothyroid elderly subjects.