UNOPERATED AORTIC-ANEURYSM - A SURVEY OF 170 PATIENTS

Citation
Mj. Perko et al., UNOPERATED AORTIC-ANEURYSM - A SURVEY OF 170 PATIENTS, The Annals of thoracic surgery, 59(5), 1995, pp. 1204-1209
Citations number
24
Categorie Soggetti
Surgery
ISSN journal
00034975
Volume
59
Issue
5
Year of publication
1995
Pages
1204 - 1209
Database
ISI
SICI code
0003-4975(1995)59:5<1204:UA-ASO>2.0.ZU;2-E
Abstract
From 1984 to 1993, 1,053 patients were admitted with aortic aneurysm ( AA) and 170 (15%) were not operated on. The most frequent reason for n onoperative management was presumed technical inoperability. Survivals for patients with thoracic, thoracoabdominal, and abdominal AA were c omparable. No significant differences in survival for patients with di ssecting and nondissecting AA were detected. In all, 132 patients (78% ) died and 78 (59%) of them died of rupture. Mean time to rupture was 1,300 +/- 8 days. Cumulative 5-year hazard of rupture for the dissecti ng AA was twice that of the nondissecting (p < 0.001). Hazards of rupt ure for type A and B dissections were comparable. Diameter of 6 cm or greater was associated with a fivefold increase in cumulative hazard o f rupture (p < 0.001). Diameter of AA, incidence of renal failure, and arterial hypertension were predictive of mortality, whereas the first two variables were predictive of rupture. In conclusion, because the majority of patients in all subgroups died of rupture, all patients sh ould be recognized as candidates for surgical treatment. Present data justify aggressive approach to the patient with AA 6 cm or more in dia meter and type A dissections. The results suggest that type B dissecti ons may have a more favorable course if operated on, but a prospective , randomized study is necessary to confirm this observation. We believ e that older patients and those with a small aneurysm may benefit from early, elective operation.