Ja. Blumenthal et al., METHODOLOGICAL ISSUES IN THE ASSESSMENT OF NEUROPSYCHOLOGIC FUNCTION AFTER CARDIAC-SURGERY, The Annals of thoracic surgery, 59(5), 1995, pp. 1345-1350
This report reviews critical issues facing investigators interested in
neuropsychologic sequelae after cardiac operations: (1) experimental
design; (2) selective attrition; (3) selection of instruments; (4) mod
erating factors; (5) definitions of cognitive decline; (6) statistical
analysis; and (7) clinical significance. Implications for further res
earch in the area are discussed.