PYODERMA-GANGRENOSUM IN 2 PATIENTS WITH MALIGNANT BLOOD-DISEASE

Pyoderma gangrenosum (PC) associated with malignant hematological dise ases in two patients is here described. One patient had acute myelomon ocytic leukemia (AMML) and the PG was limited after chemotherapy for t he leukemia. The second patient had primary thrombocytosis (PT) treate d with hydroxyurea. In this woman PG did not improve after discontinua tion of hydroxyurea. Systemic corticosteroids and azathioprine were gi ven but without response. Finally, both patients died and possibly PG in such patients can be considered as a bad prognostic factor.