PLASMACYTOMA OF THE NASAL CAVITY WITH LAMBDA-III AMYLOID DEPOSITION

Authors
EILAM O LIEPNIEKS JJ WEISBERGER E BENSON MD
Citation
O. Eilam et al., PLASMACYTOMA OF THE NASAL CAVITY WITH LAMBDA-III AMYLOID DEPOSITION, AMYLOID-INTERNATIONAL JOURNAL OF EXPERIMENTAL AND CLINICAL INVESTIGATION, 2(1), 1995, pp. 31-35
Citations number
23
Categorie Soggetti
Biology
Journal title
AMYLOID-INTERNATIONAL JOURNAL OF EXPERIMENTAL AND CLINICAL INVESTIGATION → ACNP
ISSN journal
13506129
Volume
2
Issue
1
Year of publication
1995
Pages
31 - 35
Database
ISI
SICI code
1350-6129(1995)2:1<31:POTNCW>2.0.ZU;2-8
Abstract
A patient presented with a large nasal plasmacytoma that involved the palate, ethmoid and maxillary sinuses and contained deposits of amyloi d. Immunoglobulin (AL) amyloid was found in the tumor. Amyloid fibrils extracted from the resected tumor were found to contain lambda light chain protein. Complete sequence analysis identified the protein as la mbda III immunoglobulin light chain. Evaluation of the patient failed to reveal any sign of systemic amyloidosis and three years of follow-u p has shown no evidence of recurrence.