Jo. Willoughby et al., DISTRIBUTION OF SOMATOSTATIN IMMUNOREACTIVITY IN SHEEP HYPOTHALAMUS -A COMPARISON WITH THAT OF THE RAT, Archives of histology and cytology, 58(1), 1995, pp. 31-36
The distribution of somatostatin immunoreactivity was determined throu
ghout the hypothalamus of the sheep and comparisons were made with the
known distribution of somatostatin immunoreactivity in the rat. Immun
opositive perikarya were present in the sheep periventricular region f
rom as far rostral as the supraoptic recess of the third ventricle to
the posterior optic chiasm. In the basal hypothalamus, a thick shell o
f immunopositive neurons surrounded the ventromedial nucleus (VMH), an
d there were also neurons in the caudal arcuate nucleus. Somatostatin
immunoreactive fibres were concentrated in the dorsal VMH and arcuate
nucleus as well as in the median eminence. The distribution in sheep w
as similar to that in rats, but immunoreactive neurons around sheep VM
H were distinctive, a characteristic that might relate to differences
in growth hormone physiology in this species.