SPLIT FOOD AND DEVELOPMENTAL RETARDATION ASSOCIATED WITH A DELETION OF 3 MICROSATELLITE MARKERS IN 7Q21.2-Q22.1

Authors
MARINONI JC STEVENSON RE EVANS JP GESHURI D PHELAN MC SCHWARTZ CE
Citation
Jc. Marinoni et al., SPLIT FOOD AND DEVELOPMENTAL RETARDATION ASSOCIATED WITH A DELETION OF 3 MICROSATELLITE MARKERS IN 7Q21.2-Q22.1, Clinical genetics, 47(2), 1995, pp. 90-95
Citations number
30
Categorie Soggetti
Genetics & Heredity
Journal title
Clinical genetics → ACNP
ISSN journal
00099163
Volume
47
Issue
2
Year of publication
1995
Pages
90 - 95
Database
ISI
SICI code
0009-9163(1995)47:2<90:SFADRA>2.0.ZU;2-5
Abstract
A deletion of 7q21.2-q22.1 has been found in a patient with split foot and developmental retardation. Molecular analysis using polymerase ch ain reaction (PCR) showed deletion of three microsatellite markers, D7 S527, D7S479 and D7S554, in the patient's paternal chromosome. These r esults pinpoint the critical region for an ectrodactyly locus (SHFD1) on chromosome 7.