THE JOINT, A REDOX-SENSITIVE MICROENVIRONMENT - AN HYPOTHESIS

Authors
SAHINOGLU T STEVENS CR BLAKE DR
Citation
T. Sahinoglu et al., THE JOINT, A REDOX-SENSITIVE MICROENVIRONMENT - AN HYPOTHESIS, Scandinavian journal of rheumatology, 1995, pp. 131-136
Citations number
20
Categorie Soggetti
Rheumatology
Journal title
Scandinavian journal of rheumatology → ACNP
ISSN journal
03009742
Year of publication
1995
Supplement
101
Pages
131 - 136
Database
ISI
SICI code
0300-9742(1995):<131:TJARM->2.0.ZU;2-U
Abstract
Antioxidant depletion in a normal adult increases the risk of developi ng rheumatoid arthritis (1). We discuss how redox processes ''control' ' the inflammatory reaction and suggest that the synovium is a peculia rly ''redox-sensitive'' microenvironment. This discussion will be illu strated by a zonal model of tissue injury to represent the diseased sy novium.