Aims and background: The aim of this work is to demonstrate the useful
ness of carbon dioxide, used as contrast agent, in special indications
in vascular interventional oncological procedures. Methods: We studie
d 40 patients with digital subtraction angiography enhanced with CO2 a
s a contrast agent. At the same time we utilized also, in all cases, j
odinated contrast agent to evaluate the different opacification gradie
nt, the different viscosity range and the different perfusion. Results
: The low viscosity of CO2 allows demonstration of the presence of eve
n minimal blood losses in gastrointestinal tumors and enhances arterio
venous shunts in hepatocellular carcinoma. Carbon dioxide can also be
employed to assess the patency of small-sized catheters for chemothera
py infusion which do not allow easy injection of the traditional iodin
ated contrast agents characterized by high viscosity. Conclusion: Carb
oangiographic study combined to digital subtraction angiography can de
ar some diagnostic problems and is further method to assess the outcom
e of angiographic interventional procedures in oncology.