STEROIDAL SAPONINS FROM THE BULBS OF TRITELEIA-LACTEA AND THEIR INHIBITORY ACTIVITY ON CYCLIC-AMP PHOSPHODIESTERASE

Authors
MIMAKI Y NAKAMURA O SASHIDA Y NIKAIDO T OHMOTO T
Citation
Y. Mimaki et al., STEROIDAL SAPONINS FROM THE BULBS OF TRITELEIA-LACTEA AND THEIR INHIBITORY ACTIVITY ON CYCLIC-AMP PHOSPHODIESTERASE, Phytochemistry, 38(5), 1995, pp. 1279-1286
Citations number
25
Categorie Soggetti
Plant Sciences
Journal title
Phytochemistry → ACNP
ISSN journal
00319422
Volume
38
Issue
5
Year of publication
1995
Pages
1279 - 1286
Database
ISI
SICI code
0031-9422(1995)38:5<1279:SSFTBO>2.0.ZU;2-D
Abstract
The chemical compounds in the bulbs of Triteleia lactea have been anal ysed as a part of our systematic study of plants of the subfamily Alli oideae in Liliaceae. Thirteen steroidal saponins, seven of which appea red to be new compounds, were isolated. The structures of the new sapo nins were elucidated on the basis of the spectroscopic analysis, inclu ding two-dimensional NMR techniques, and hydrolysis. Inhibitory activi ty of the isolated saponins on cyclic AMP phosphodiesterase was evalua ted to identify new compounds with medicinal potential.