Y. Mimaki et al., STEROIDAL SAPONINS FROM THE BULBS OF TRITELEIA-LACTEA AND THEIR INHIBITORY ACTIVITY ON CYCLIC-AMP PHOSPHODIESTERASE, Phytochemistry, 38(5), 1995, pp. 1279-1286
The chemical compounds in the bulbs of Triteleia lactea have been anal
ysed as a part of our systematic study of plants of the subfamily Alli
oideae in Liliaceae. Thirteen steroidal saponins, seven of which appea
red to be new compounds, were isolated. The structures of the new sapo
nins were elucidated on the basis of the spectroscopic analysis, inclu
ding two-dimensional NMR techniques, and hydrolysis. Inhibitory activi
ty of the isolated saponins on cyclic AMP phosphodiesterase was evalua
ted to identify new compounds with medicinal potential.