The objective of this study was an evaluation of the prevalence of myo
pathies in paediatric patients scheduled for orthopaedic surgery (club
foot) performed under regional anaesthesia. Seventeen infants schedule
d for lower limb orthopaedic surgery were studied to verify coexisting
neuromuscular disorders with electromyography and muscle biopsy durin
g surgery. All surgical procedures were performed under caudal block o
r spinal anaesthesia, associated with light general anaesthesia. No ma
jor cardiorespiratory, neurological or malignant hyperthermic complica
tions (muscle rigidity, arrhythmias, hyperpyrexia) were observed. Comb
ined neurological, electromyographic and biopsy studies showed a high
rate of myopathic changes (70%). Performance of clubfoot surgery under
light general anaesthesia with regional techniques was free from any
problems. The high rate of myopathic changes (70%) observed in the mus
cle biopsies suggests that precautions should be taken with paediatric
patients for clubfoot surgery and a regional anaesthesia technique wi
th adequate monitoring may be helpful to prevent possible malignant hy
perthermia related problems.