Indium-111 labelled platelet scintigraphy permits simple, accurate eva
luation of platelet kinetics and sites of deposition. The most meaning
ful results are obtained from serial scans, although these are clinica
lly useful in only a few of the many applications that have been sugge
sted, principally in studies of acute thrombosis, prosthetic graft thr
ombogenicity and antiplatelet medication. Key pitfalls are associated
with selection of regions and patient variation.