In a prospective, randomized, blind study, we assessed the effectivene
ss of droperidol 20 mu g kg(-1) i.v., given at induction of anaesthesi
a, in preventing postoperative vomiting in paediatric day-case patient
s. We studied 270 children, aged 1-15 yr, undergoing body surface surg
ery. There was a significant reduction in the incidence of vomiting in
the recovery room (1.4% vs 9.2%, P < 0.005) and in the day ward (9.4%
vs 18.3%, P < 0.05) in patients receiving droperidol. There was no si
gnificant difference on the journey home (9.5% vs 17.83%, ns) or at ho
me (16.7% vs 10.3%, ns). There was also a reduction in the severity of
vomiting in the droperidol group. There were no adverse side effects.