M. Schmidt et al., COURSE OF PATIENTS DIAGNOSED AS HAVING SCHIZOPHRENIA DURING FIRST EPISODE OCCURRING UNDER AGE 18 YEARS, European archives of psychiatry and clinical neuroscience, 245(2), 1995, pp. 93-100
Of 118 child and adolescent schizophrenic patients (ICD-9: 295.x; mean
onset age 16.0 years), 97 (82.2%) could be completely investigated at
follow-up (mean interval 7.4 years; mean age 23.1 years). At followup
30% of the patients were semidependent or dependent, 72% still requir
ed psychiatric treatment, 44% were at least moderately impaired with r
egard to educational/occupational functions and 58% with regard to soc
ial functions; 73% had experienced at least one further schizophrenic
episode. Comparison with schizophrenia beginning in adulthood showed t
hat the impairment in social function was much greater in the younger
group of patients. These results support the belief that schizophrenic
psychoses starting in adolescence have a worse outcome than those beg
inning in adulthood. The most efficient indicators for a worse outcome
were long duration of inpatient treatment at first admission, a high
number of symptoms and low social competence at discharge.