A chart analysis for a 5-year period through December 1992 identified
four full-term neonates with lobar hemorrhage. Prenatal and obstetrica
l histories were uncomplicated; all infants presented with seizures wi
thin 48 h following birth. Perinatal asphyxia and isoimmune thrombocyt
openia were associated with lobar hemorrhage in two children. Although
computed tomography was sufficient for diagnosis, magnetic resonance
evaluation provided assessment of specific cortical injury and the age
of the hemorrhage. No infant underwent surgical intervention; three c
hildren reached developmental milestones at a mean follow-up of 3.3 ye
ars.