Ml. Galyean et al., EFFECTS OF ARRIVAL MEDICATION WITH TILMICOSIN PHOSPHATE ON HEALTH ANDPERFORMANCE OF NEWLY RECEIVED BEEF-CATTLE, Journal of animal science, 73(5), 1995, pp. 1219-1226
Three trials were conducted to evaluate delete ate the use of tilmicos
in phosphate (Micotil(R)) as a prophylactic medication for newly recei
ved, stressed beef cattle. In Trial 1, 57 beef calves (average initial
BW = 170 kg) were shipped to the research feedlot from Tennessee and
either given no antibiotic at processing or treated with Micotil at 10
mg of tilmicosin phosphate/kg of BW. During a 28-d receiving period,
treatment at processing with Micotil did not affect daily gain (P <.17
) or DMI (P <.22) compared to control calves. Prophylactic treatment w
ith Micotil decreased (P <.01) the percentage of calves treated for sy
mptoms of bovine respiratory disease from 46.4 to 0%. In Trial 2, 117
calves (average initial BW = 198 kg) were shipped from Tennessee and a
llotted randomly to the same two treatments as in Trial 1. All calves
grazed a 24-ha pasture of irrigated winter wheat during the 28-d recei
ving period. Treatment of calves with Micotil at the time of arrival p
rocessing did not affect (P >.50) daily gain during the trial; however
, as in Trial 1, mass treatment with Micotil decreased (P <.01) the pe
rcentage of calves treated for respiratory disease from 46.4 to 0%. In
Trial 2, 117 calves (average initial BW = 191 kg) were shipped from T
ennessee and allotted randomly to the same two treatments as in Trial
1. All calves grazed a 24-ha pasture of irrigated winter wheat during
the 28-d receiving period. Treatment of calves with Micotil at the tim
e of arrival processing did not affect (P >.50) daily gain during the
trial; however, as in Trial 1, mass treatment with Micotil decreased (
P <.01) the percentage of calves treated for respiratory disease from
32.8% to 12.1%. In trial 3, two truckloads of beef calves (183 total;
average initial BW = 232 kg) shipped from Tennessee were allotted rand
omly to the same two treatments used in Trials 1 and 2 or to a third t
reatment that consisted of administration of Micotil at arrival proces
sing if the rectal temperature of the calf was greater than or equal t
o 39.7 degrees C. Treatment at arrival processing with Micotil, whethe
r on a mass basis or based on rectal temperature, increased daily gain
during the initial 28-d receiving period (P <.01) and a subsequent 28
-d feeding period (P <.07). Dry matter intake was greater (P <.05) and
feed:gain ratio was lower (P <.03) for both groups of Micotil-treated
calves than for control calves for the overall 56-d trial. Both mass
treatment (11.9%) and rectal temperature-based treatment (12.9%) of ca
lves with Micotil decreased (P <.01) the percentage of calves treated
for respiratory disease compared with controls (43.6%). Micotil seems
to be a highly effective prophylactic medication for newly received be
ef cattle that have been subjected to shipping stress. Application of
Micotil based on rectal temperature of calves at the time of processin
g was as effective as mass treatment.