The role of attachment in interaction with other relationships and con
ditions was investigated in relation to children's later psychosocial
development (at ages 6 and 9). Thirty-nine unipolar depressed mothers,
24 bipolar mothers, and 32 normal control mothers and their children
were studied. The network of conditions defining early experience incl
uded, in addition to attachment, maternal psychopathology, marital dis
cord, other disordered relationships in the family, and recent losses
of significant persons. Patterns of mother-child interaction were also
examined. Assessments of children's problems were based on psychiatri
c evaluations of depressive affect, anxiety, and disruptive-opposition
al behavior. The findings support the conclusion that attachment enter
s into development in interaction with other relationships and conditi
ons. Maternal psychopathology, in particular, in interaction with the
attachment relationship, is linked to later developmental outcomes. Th
e importance of considering mother-child interactional and disposition
al characteristics is indicated. The early attachment relationship tog
ether with the ways in which the mother's depression is expressed with
her child, and the child's style of coping with the mother's function
ing establish patterns of behavior that influence the child's vulnerab
ility to later problems. Multiple pathways of transmission of affectiv
e problems are discussed.