SYNTHESIS AND IN-VITRO PROFILE OF 7-SUBSTITUTED QUINOLINE CHROMANOLS AS NOVEL, NONACIDIC LTB(4) ANTAGONISTS

Authors
MASAMUNE H BRESLOW R CHENG JB CONKLYN MJ EGGLER JF MARFAT A MELVIN LS PILLAR JS SHIRLEY JT SHOWELL HJ TICKNER JE
Citation
H. Masamune et al., SYNTHESIS AND IN-VITRO PROFILE OF 7-SUBSTITUTED QUINOLINE CHROMANOLS AS NOVEL, NONACIDIC LTB(4) ANTAGONISTS, Bioorganic & medicinal chemistry letters, 5(8), 1995, pp. 887-892
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
8
Year of publication
1995
Pages
887 - 892
Database
ISI
SICI code
0960-894X(1995)5:8<887:SAIPO7>2.0.ZU;2-H
Abstract
The development of novel LTB(4) antagonists from a class of quinolylme thyl LTD(4) antagonists is described. These alpha-methyl quinolylmethy l chromanols were found to have good in vitro activity.