A. Stijkel et L. Reijnders, IMPLEMENTATION OF THE PRECAUTIONARY PRINCIPLE IN STANDARDS FOR THE WORKPLACE, Occupational and environmental medicine, 52(5), 1995, pp. 304-312
The objectives were to describe and discuss the current and proposed E
uropean occupational health policy on two categories of substances tha
t pose serious effects: those potentially carcinogenic or genotoxic an
d those with toxic effects on reproduction. The precautionary principl
e was applied to setting standards for the workplace for those two cat
egories of substances, to give an impression of the resulting limit va
lues and the consequences of the implementation of this precautionary
principle. A pragmatic approach was chosen as this starts with substan
tial indications of health risks. For the suspected carcinogenic or ge
notoxic substances 0.1 mg/m(3) as a precautionary occupational exposur
e limit (precautionary OEL) is proposed. For the substances suspected
of causing reproductive toxicity the precautionary OEL was derived in
three ways, depending on the availability of data and of a current Dut
ch workplace standard (MAC, maximum accepted concentration): (a) by ca
lculation based on available inhalatory animal data on the risks of re
productive toxicity; (b) by adding a safety factor of 10 to the curren
t MAC, if no inhalatory animal data on reproductive toxicity are avail
able; (c) by using 0.1 mg/m(3) as precautionary OEL for substances sus
pected of having reproductive toxicity but without inhalatory animal d
ata on reproductive toxicity and without a MAC.